DSIP (Delta Sleep-Inducing Peptide): Better Sleep Without Sedation
DSIP peptide normalizes sleep architecture without sedation. Learn how delta sleep-inducing peptide improves deep sleep, reduces cortisol, and proper dosing.
Novo Pharma Research Team
Novo Pharma Research · peer-reviewed literature synthesis
DSIP (Delta Sleep-Inducing Peptide): Better Sleep Without Sedation
References:
- Schoenenberger GA, Monnier M. Characterization of a delta-electroencephalogram-sleep-inducing peptide. Proc Natl Acad Sci USA. 1977;74(3):1282-1286.
- Graf MV, Kastin AJ. Delta-sleep-inducing peptide (DSIP): a review. Neurosci Biobehav Rev. 1984;8(1):83-93.
- Kovalzon VM, Strekalova TV. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. J Neurochem. 2006;97(2):303-309.
- Xie L, Kang H, Xu Q, et al. Sleep drives metabolite clearance from the adult brain. Science. 2013;342(6156):373-377.
- Schneider-Helmert D, Schoenenberger GA. Effects of DSIP in man: multifunctional psychophysiological properties. Neuropsychobiology. 1983;9(4):197-206.
- Prudchenko IA, Stashevskaya OS, Mikhaleva II, Ivanov VT. DSIP and its analogues: opioid-like effects. Bioorg Khim. 1996;22(10-11):829-838.
- Iyer KS, Marks GA, Kastin AJ, McCann SM. Evidence for a role of delta sleep-inducing peptide in slow-wave sleep and sleep-related growth hormone release. Proc Natl Acad Sci USA. 1988;85(10):3653-3656.
- Schneider-Helmert D. Effects of DSIP on narcolepsy and on disturbed and normal sleep. Eur Neurol. 1984;23(5):357-363.
- Dick P, Grandjean ME, Bhattacharya JF, et al. DSIP in the treatment of withdrawal syndromes from alcohol and opiates. Eur Neurol. 1984;23(5):364-371.
- Larbig W, Gerber WD, Kluck M, Schoenenberger GA. Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes. Eur Neurol. 1984;23(5):372-385.
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